Quantitative Methods in Chemistry
NPTEL is offering online course for undergraduate students in Quantitative Methods in Chemistry.
About the course:
Enrollment Ends: February 03, 2020
Exam Date: April 26, 2020
For more details, please visit: https://swayam.gov.in/nd1_noc20_cy02/preview
- This course aims to train students towards appropriate scientific reporting of the experimental data and testing hypothesis using statistical analyses.
- It emphasizes on reproducibility of experiments and the sources of “errors” during repetitions of experiments, how to quantify and minimize wherever feasible.
- In the later part, it deals with the principles of volumetric analysis, separation techniques (for instance chromatography, gravimetric analysis, etc.) employed for chemicals and bimolecular.
- Principles of instrumentation techniques will also be discussed.
- Week 1: Chemical stoichiometry, parameters to define concentration of chemicals (normality, molarity, molality, mole-fractions, parts-per million), analytical concentration and equilibrium concentrations, p-value of concentration
- Week 2: Measurements and its statistical analyses (definition of mean, median, mode, variance, standard deviation, standard error, accuracy, precision), need for performing replicates/repeats, reproducibility
- Week 3: Classification and sources of errors, error propagation, scientific reporting data (significant figures), error curves
- Week 4: Hypothesis validation (null hypothesis, confidence levels, confidence intervals, one-tail test, two-tail test, use of statistical tables such as z-table, t-table, F-table, identifying outliers in data with Q-test)
- Week 5: Sampling, fitting and analysis of data (linear regression, single factor analysis of variance, least-significant difference).
- Week 6: Software-based data analysis (linear and non-linear regression)
- Week 7: Examples of data fitting and analysis (application to rate kinetics, gradient mixing, bimolecular folding)
- Week 8: Sample preparation: concept of standards (primary and secondary), traditional methods of analysis (gravimetric, volumetric, potentiometric methods)
- Week 9: Analytical separations (solvent extraction, chemical precipitation, chromatography, types of chromatography – size exclusion, ion exchange, affinity, gas, high pressure liquid chromatography, field-flow fractionation)
- Week 10: Theoretical basis of chromatography (concept of plates, theoretical plate height, plate count, resolution, retention time, retention factor, selectivity factor)
- Week 11: Differences between rate theory and plate theory
- Week 12: Protocols with video demonstration of separation techniques
Enrollment Ends: February 03, 2020
Exam Date: April 26, 2020
For more details, please visit: https://swayam.gov.in/nd1_noc20_cy02/preview
